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However, the evidence regarding implications of DM on orthodontic tooth movement and bone remodeling is limited to animal studies.
The PDL and alveolar bone remodeling are the important parameters in tooth movement, and bone turnover is known to increase after bone grafting, fracture, and osteotomy.
However, more study on the synergistic effect on tooth movement and bone formation in response to an EP4 agonist is needed to determine its mechanisms.
The amounts of tooth movement and bone volume of the paradental region were evaluated by using soft x-ray and micro-computed tomography.
Conclusions: Our preliminary study suggests the possibilities of synergistic enhancement of the rates of tooth movement and bone formation during tooth movement through the local injection of a specific EP4 receptor agonist.
Similar(55)
To determine the possibility of synergistically enhancing orthodontic tooth movement (OTM) and bone formation in vivo by administering bone morphogenetic protein type 2 (BMP-2) on the tension side or in combination with corticotomy on the pressure side.
EP4 agonist injection in conjunction with tooth movement significantly enhanced the amounts of tooth movement and regional bone volume in the tension side compared with the vehicle-treated group (P <.05).
A protocol to measure the relative movement between implant and bone was designed to test whether or not such a measurement, if made in a laboratory, could discriminate between hip prostheses.
Although it had been reported that Ca2+-activated K+ currents are involved in the regulation of osteoclast movement and spreading on bone substrates, and that increase in intracellular Ca2+ blocks osteoclast bone resorption in vitro (Valverde et al., 2005), the specific contribution of Kcnn4 in inflammation-induced osteoclast development in vivo was not previously reported.
While it is difficult, costly or even invasive to obtain biomechanical measurements of the human body, the computational approach such as the finite element (FE) method provides an efficient and objective alternative to predict tissue deformation, interfacial pressure, joint and bone movement, internal load distribution, etc.
As seen in other RSA studies, in both groups most of the migration of the stem occurred between the stem and the cement mantle, with little movement between the cement and bone.
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