To test whether depletion of Rad52 inhibits FANCM-deficient tumor growth, we monitored tumor formation in a mouse xenograft model.
Furthermore, I-14 significantly inhibited tumor growth in Bel7404 mouse xenograft model.
Moreover, 6h could efficiently suppress human tumor growth in mouse xenograft model without causing obvious toxicities.
Nude mouse xenograft model was also used to evaluate the in vivo activity.
Compound 5 was chosen for evaluation in a nude mouse xenograft model.
Reznikov, A. G., Chaykovskaya, L. V., Polyakova, L. I. & Kornelyuk, A. I. Antitumour effect of endothelial monocyte-activating polypeptide-II on human prostate adenocarcinoma in mouse xenograft model.
Accordingly, combination therapy with carfilzomib plus chloroquine was highly effective in the treatment of MM in a mouse xenograft model.
Furthermore, LLL12 demonstrated a potent inhibitory activity on breast and glioblastoma tumor growth in a mouse xenograft model.
In a mouse xenograft model, [11C]TMP rapidly accumulated in Ec dhfr carrying cells within minutes of intravenous administration.
Importantly, these peptides can also inhibit tumor growth in a mouse xenograft model without eliciting side effects.
In a mouse xenograft model, 11 inhibited growth of human pancreatic cancer cell line PCI66 with negligible body weight loss.
