Sentence examples for mouse xenograft experiments from inspiring English sources

Next, we tested the oncogenic potential of the TRKB mutants in vivo, in mouse xenograft experiments.

Authors also acknowledge the Experimental Mouse Shared Service (EMSS), Arizona Cancer Center for carrying out the mouse xenograft experiments.

Finally, the mouse xenograft experiments should be interpreted with caution because rodent cells are inherently insensitive for CGs [19], [20].

The physiological difference between human and mouse explains the previously observed sensitivity of human cancer cells in mouse xenograft experiments.

How can this be reconciled with the published mouse xenograft experiments that show efficient cytotoxicity of grafted cells without adverse effects on the host?

In line with these findings, Perne et al. recently published experimental results suggesting that general inhibition of protein synthesis is the main mechanism of the anti-cancerous effects of CGs in human cells, and that physiological species differences may explain the previously observed sensitivity of human cancer cells in mouse xenograft experiments [20].

To answer the question that whether HOXB9 plays a similar inhibitory role in vivo as in vitro, we examined the potential blockade of HOXB9 on tumour growth and metastasis in a nude mouse xenograft experiment as designed in Figure 4A.

Combination therapy of quinacrine and paclitaxel were determined to be synergistic in both, in vitro and in vivo (mouse xenografts) experiments.

In summary, the mice xenograft experiments demonstrate that PS culture enriches in TICs both in LNCaP as well as in PCSCs.

Control, SRSF1- or SRSF9-overexpressing cell lines were established, and their tumorigenic potential were verified in anchorage-dependent colony formation assays and nude mice xenograft experiments.

Soft-agar colony formation assay and nude mice xenograft experiments demonstrated that these cells, even those with additional inactivation of p53, did not have transformed phenotypes.