We found that the lethally TB-susceptible phenotype of 129S2 mice, which resembles primary progressive TB, can be rescued by IFNAR1 deletion.
We demonstrate that applying this refined protocol we obtain mice which resemble germ-free mice in terms of hypoplastic lymphoid tissue.
Using PRG‐1+/− mice, which resemble the PRG‐1WT/mut situation present in human SNP carriers, we could show for the first time that proper bioactive lipid signaling at the synapse is important for cortical information processing.
Our study aimed at elucidating the role of PI3Kγ in the mouse model of AIA, which resembles many aspects of RA in humans.
The transcriptome data of the organogenesis embryos during organogenesis (CS9-23, which resembles the mouse organogenesis period of TS13-TS27) and zebrafish embryos during organogenesis were obtained from NCBI GEO [GSE15744 and 24840, respectively] [ 18, 57].
Deletion of ILK in mice leads to peri-implantation lethality, which resembles that of integrin β1 or PINCH1 knockouts [ 21- 24].
A liver-specific Foxo1-knockout mouse displays a lower level of plasma glucose and enhanced glucose tolerance primarily because of decreased gluconeogenesis, which resembles the phenotype of LMKO mouse.
Humans with mutations in the IR (Leprechaunism) exhibit profound growth retardation, which resembles those seen in mice with engineered mutations of the IR.
The Epson light box, which resembles a seriously overgrown computer mouse, is placed on top of a plastic negative or slide holder that sits atop the scanner's glass.
Treatment of wild-type mice with a general MMP inhibitor, GM6001, caused delayed cartilage remodeling and bone formation during fracture repair, which resembles the defect observed in Mmp9 –/– mice.
