Your English writing platform
Discover LudwigExact(20)
A similar finding was described previously when comparing cultured wildtype mouse fibroblasts to fibroblasts from the rd16 mouse, which expresses a microtubule-binding deficient variant of CEP29026.
To understand how neurons cope with polyQ toxicity, we studied a Spinocerebellar ataxia 7 (SCA7) mouse which expresses polyQ-expanded ATXN7 only in rod photoreceptors.
We showed that a well-characterized Foxp3gfp reporter mouse, which expresses an N-terminal GFP-Foxp3 fusion protein, is a hypomorph that causes profoundly accelerated autoimmune diabetes on a NOD background.
The objective of this study, is to elucidate the in vivo immunomodulatory role of IFN-I signaling in T cells during EAE using a novel transgenic mouse, which expresses functional type I IFN receptor (IFNAR1) exclusively on T lymphocytes (IFNAR1Texcl).
We then tested these "conditional AAVs" (AAV-LS1L-GFP; AAV-LS2L-RFP) using two different Cre knockin drivers, the Pv-cre mouse, which expresses Cre in parvalbumin-containing (PV+) GABAergic neurons [23], and the Emx-cre mouse, which expresses Cre in glutamatergic neurons in the forebrain [24].
Finally, transgenic mouse models have been engineered to mimic celiac disease, most notably the NOD Ab° DQ8+ mouse, which expresses human DQ8 in an endogenous MHC class II-deficient (Ab°), autoimmune-prone (NOD) background [36].
Similar(40)
To evaluate the role of RIPA in viral pathogenesis, we engineered a genetically targeted mouse, which expressed a mutant IRF-3 that was RIPA-competent but transcriptionally inert; this single-action IRF-3 could protect mice from lethal viral infection.
Experiments were also performed in the GAD67-GFP mouse which expressed GFP fluorescence in some Type III taste cells.
Bnc1 mice were obtained by mating the Bnc1 (+/fl-neo) with a ZP3-Cre mouse, which expressed Cre recombinase only in the oocytes [35].
Higher binding was observed compared with that seen in APP/PS1 mice, which expresses the Swedish APP and presinilin-1 transgene (Alzheimer-like amyloid pathology model).
To generate mice deficient of GSNOR only in cells of the hematopoietic lineage, we crossed GSNORf/f mice with Vav-cre transgenic mice, which expresses the Cre recombinase mostly in the hematopoietic cells including inflammatory cells (27).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com