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Data from one female WT mouse were excluded from the behavioral analysis due to technical problems with video recording.
Values from the Yellow mouse were excluded from calling regions.
ASL data of one treated mouse were excluded due to large image distortion and DCE data of one control mouse were excluded due to technical issues.
ASL data of one mouse were excluded from the control group due to inferior image quality.
As this may have been a tissue preparation error, all western blot data from this mouse were excluded from the final results.
Samples of 1 Per35/5 and 1 WT mouse were excluded from further analyses because of the poor quality of the arrays, based on the output of the Agilent feature extraction.
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A single mouse was excluded from the analyses because the model fit yielded non-physiological parameter estimates.
A mouse was excluded from the study if clear margins were not attainable.
One male SOD1G93A mouse was excluded owing to death from non-neurological disease.
One mouse was excluded from the db/+, fasted group due to technical difficulties with anesthesia.
To minimize potential confounding effects, the yellow mouse was excluded from the differential methylation calling presented below.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com