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A second Pol β Tg mouse was developed but this model only expresses Pol β in the thymus and elevated tumor formation was not observed [59].
Since the Rgs2 null mouse was developed in the C57Bl/6 background, we injected Rgs2−/− mice and C57BL/6 wild type controls with syngeneic 3LL cells subcutaneously in the hindlimb, and measured tumor growth over time.
The mFwe knock-out mouse was developed using genOway technical services (genOway, France).
The GHRKO mouse was developed as an animal model for Laron syndrome that affects humans (Zhou et al., 1997).
The asj mouse was developed at The Jackson Laboratory as part of the ENU mutagenesis program (http://mousemutant.jax.org/articles/mmrmutantasj.html).org/articles/mmrmutantasj.html
In this regard, it was interesting that a HLA-B*5101 HLA-B*5101n transgenic mouse was developed [ 15].
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Later, the same device but adapted for mice was developed [29].
However, a mouse model of Salmonella colitis in streptomycin-pretreated mice was developed more than fifty years ago by Bohnhoff [12].
A line of mice was developed and examined that was termed the Shortstop mouse (9).
An intratumoural aromatase model system in mice was developed to mimic postmenopausal ER+ breast cancer.
Recently, however, a NASH-HCC mouse model, named STAM mice, was developed using neonatal exposure to streptozotocin and continuous high-fat diet feeding.
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