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After each mouse trial, the arena was thoroughly cleaned to minimize olfactory cues.
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In our mice trial, the median TTP was 59 days for the alternated sequences of treatment, which represent a 64% increased compared with the mTTP of sunitinib.
The arena and objects were cleaned with 70% ethanol after each mouse trial to prevent the build-up of olfactory cues.
"We had Mickey Mouse trials in the past and we saw the results.
Millions have been pumped into potential cures that might work at the mouse trial level, but fail when applied to humans.
It is possible that environmental enrichment may confound mouse trials by increasing the heterogeneity of the clinical and neuropathological phenotype [14].
Within a year of the mouse trials, sufficient penicillin was being harvested to treat a few human beings.
It was the configuration used during in vivo mouse trials.
The vertical, dotted line indicates the mean learning trial across mice (trial 26).
The number of squares entered within the allotted time was noted per mouse per trial; as the experiment is contingent upon the novelty of the aberrant context, each subject was only tested once.
On each trial, the mouse was placed into the tank at one of four designated start locations and allowed to find and escape onto the platform.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com