Sentence examples for mouse transgenic for from inspiring English sources

LCMV-specific peptide tolerisation of CD4+ T cell helper function was analyzed by adoptively transferring 5×104 indicator splenocytes from a mouse transgenic for a T cell receptor recognizing the LCMV helper epitope GP61 (LCMV-glycoprotein61-80/I-Ab-specific TCR, SMARTA mice) into naïve C57BL/6 mice.

AML-12 cell line was established from hepatocytes from the mouse transgenic for human TGF- α.

We then generated mice transgenic for the c06 BAC transgene that also carried the T hp deletion on B6.YAKR.

We obtained the Tg tetL 1Bjd/J strain of mice, transgenic for a TRE-regulated luciferase transgene, from Jackson Laboratories.

CD34+ HSPC were transduced with the F5 TCR lentiviral vector or mock transduced and transplanted into neonatal NSG mice or NSG mice transgenic for human HLA-A*0201 HLA-A*0201

Immunization of wild-type mice and mice transgenic for HLA-A2.1 with the peptide mix successfully induced both humoral and cell mediated immune responses.

Twenty-four mice mice transgenic for human CuZnSOD, resulting in overexpression of the cytosolic enzyme, were compared with 11 matched controls over 19 months.

Here we report on our analysis of a set of mice transgenic for a modified yeast artificial chromosome carrying the human PAX6 locus.

It has also been shown to rescue the manic-like behavior of mice transgenic for GSK3β and Clock (Prickaerts et al. 2006; Jope and Roh 2006; Roybal et al. 2007).

A DNA vaccine encoding human carcinoembryonic antigen (CEA) broke peripheral T-cell tolerance toward this tumor self-antigen expressed by Lewis lung carcinoma stably transduced with CEA in C57BL/6J mice transgenic for CEA.

Using mast cells from mice transgenic for human FcγRIIb, we show that this tandem Fc binds with high affinity to murine FcɛRI and human FcγRIIb on mast cells, triggers phosphorylation of FcγRIIb, and inhibits FcɛRI-dependent calcium mobilization.