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Herein, we crossed a CD19cre and PTENfl/fl mouse to generate a conditional PTEN knockout mouse in the CD19+ B cell compartment.
For example, transgenic technology that has been widely used in mouse to generate cardiac hypertrophy models shall be adapted in zebrafish [8], [30].
We crossed the floxed Pkd1flox/flox or Kif3aflox/flox mouse with CMV-Cre mouse to generate global Pkd1 (CMV-Cre Pkd1+/Δ) CMV-Cre Pkd1+/Δzygors (CMV-Cre;Kif3a+/Δ) mice.
This Msh2−/−Msh6+/− mouse was bred with a wild type C57BL/6 mouse to generate Msh2+/−Msh6+/− mice in which the defective Msh2− and Msh6− genes were in cis (Figure 1).
A BALB/c deaf14/deaf14 mouse was crossed to a C57BL/6+/+ mouse to generate N1 offspring, which were intercrossed to produce 140 N1F1 offspring.
A total of 5 × 106 MDA-MB-453 cells were injected into the flank of each mouse to generate the xenograft tumors [ 9].
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SR/CR F1 Nos2+/- mice were crossed with WT Nos2-/ mice to generate the BC generation.
The TTC9A chimeras were crossed to C57BL6/6J mice to generate TTC9A heterozygous mice.
We crossed these mice to generate LFA-1 FRET CD11a-mYFP/CD18-mCFP CD11a-mYFP/CD18-mCFP CD11a-mYFP/CD18-mCFPFP) mice (Fig. S1C).
METHODS: Polyoma Middle T Antigen mice were crossed to the human MUC1.Tg mice to generate MMT mice.
Oxtr f/f mice were crossed to CaMKIIα-Cre mice to generate Oxtr conditional knockout (Oxtr −/−) mice in the C57BL/6 genetic background.
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