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We used a well-characterized model of vascular toxicity, the apolipoprotein E knockout (ApoE−/−) mouse, to assess comparative responses to these atmospheres.
We next examined the performance of each mouse, to assess which individual mice learned the task, and if so, at what trial number in the training session.
The entire lengths of the scaffold/cartilage or cartilage/cartilage (for controls) were measured with a cursor using a computer mouse to assess the integration.
We further validated these findings by using a proteasome reporter mouse to assess ubiquitin-mediated degradation of a full length and endogenously expressed proteasomal substrate in aged lung tissue.
3D ROI's were created for heart, lung, liver, spleen, kidneys and bladder at each time point using InviCRO 3D and the counts decay corrected and compared to the total injected at the 40 min time point for each mouse to assess biodistribution and clearance.
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In mice SUVbrain was compared between Mdr1a/1b dKO and WT mice to assess whether [11C]flumazenil is a P-gp substrate (genetic disruption model).
We used genetically engineered mice in which the diphtheria toxin (DT) receptor is targeted to Langerhans cells (Lang-DTR mice) to assess sensory axon dendritic cell interactions.
We performed in vivo electrophysiological studies of freely behaving Fmr1-KO mice to assess neural activity, in the form of single-unit spiking and local field potential (LFP), within the hippocampal CA1 region during multiple differentiated sleep and wake states.
Therefore, the present study was devised in aging mice to assess the antiimmunosenescence potential from the consumption of milk that is fermented with probiotic Lactobacillus fermentum MTCC 5898 (LF).
For this purpose, we designed an allergen-driven rechallenge model of allergic airway inflammation in mice, to assess the effectiveness of tiotropium and the long-acting β-2 adrenoceptor agonist olodaterol on allergen-induced exacerbations of airway disease.
Regions of interest were manually drawn around the bodies of the mice to assess signal intensity emitted.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com