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RNA was detected in all newborn mouse tissues tested but was decreased during postnatal development.
CLIMP-63 mRNA expression was detected in all mouse tissues tested by RT-PCR, and was lower in the kidney compared with most other tissues.
Despite being a minor determinant of protein evolution in multicellular organisms, low protein expression of ERK1 could play a role in the faster evolution rate of ERK1 since ERK1 is expressed usually at lower levels than ERK2 (in brain from marsupial to mouse Additional file 2D, and in nearly all mouse tissues tested Additional file 4).
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In particular, Hmga2 has not been detected in any of the adult mouse and human tissues tested, apart from a very low expression in CD34-positive hematopoietic stem cells, mouse preadipocytic proliferating cells and meiotic and post-meiotic cells (secondary spermatocytes and spermatids) (Chieffi et al., 2002).
As shown in Figure 2, the shift in the highest peak compared to tail (panel A) and the instability index (panel B) were highly reproducible between mice for all tissues tested.
The transcription factor components in ACT::DBD-TAD mice were expressed in all tissues tested, although the expression level varied amongst different tissues (Fig. 6C).
In multiple adult tissues tested, Cobra1+/− mice produced approximately half the amount of Cobra1 mRNA and protein that their wild-type littermates did (Fig. S1B and S1C; data not shown).
However, residual COX activity in tissues tested in the mice ranged between approximately 50% and 80%, with brain close to 80%.
And the 6 miRNAs present only in the mouse genome are expressed in the 4 tissues tested.
Cystathionine β-synthase−/− knockout mice exhibit severe hyperhomocysteinemia and accumulate AdoHcy in all tissues tested [53,140].
Previous analysis of Npm3 expression in mouse tissues also showed generally equal and strong expression in the tissues tested with especially strong expression in testis [ 21].
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