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RT-PCR analysis of linc-MD1 in mouse tissues indicates that it is highly expressed in skeletal muscles of dystrophic mdx animals (TIB and SOL), paralleling miR-206 and miR-133b synthesis.
Expression profiling for multiple human and mouse tissues indicates correlations between expression of certain Rabs and the SNAREs, adaptors, and other proteins with which they interact [ 17] and facilitates construction of potential interaction hubs and prediction of novel pathways.
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Quantitative RT-PCR from mouse tissues indicated strongest EH3 expression in lung, skin, and upper gastrointestinal tract.
Thorough analyses of RNA-seq data from early developing thymocytes and other mouse tissues indicated that long-range bidirectional transcription is an intrinsic property of a class of promoters whose associated genes mainly encode for transcriptional regulators involved in development and cell differentiation.
Quantitative RT-PCR from mouse tissue indicated that the novel membrane-bound EH3 was among 20 organs investigated most highly expressed in skin and stomach.
Western blot studies of adult mouse primary tissues indicate p140Cap expression in brain, testis and epithelial-rich tissues including lung, kidney and mammary glands (Di Stefano et al, 2004).
Experiments were performed in triplicate or tetraplicate from two or three independent cell cultures or from chicken and mouse tissues as indicated below.
SMN protein was not detectable in the SMA mouse tissues analyzed, indicating that very little SMN protein is produced from the h SMN2 gene (Fig. 1B).
The increased expression of CD31 and VEGF in tumor tissues indicates that tumor angiogenesis increased in the HFD-fed mice.
Moreover, Rspo1 significantly reduced DSS-induced myeloperoxidase activity and inhibited the overproduction of proinflammatory cytokines, including tumor necrosis factor-α, IL-1α, IL-6, interferon-γ, and granulocyte-macrophage colony stimulating factor, in mouse intestinal tissue, indicating that Rspo1 may reduce DSS-induced inflammation by preserving the mucosal barrier function.
H3K9 hyperacetylation in the S. aureus infected mice tissue also indicates plausible role of PCAF (KAT2B), which could be explored further.
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