Sentence examples for mouse thyroids after from inspiring English sources
Additionally, we have shown that regulation of Klk1 and Klk1-related genes in mouse thyroids after 131I exposure does not show a circadian variation [32].
Furthermore, 18/31 transcripts with protein expression, 5/16 transcripts with no protein expression, and 20/83 transcripts having unknown protein expression in normal human thyroid tissue were up-regulated at the RNA level in mouse thyroids after exposure to 1.4 Gy, but down-regulated at the other four absorbed doses.
The present study represents a multifaceted and extensive approach to investigate the transcriptional changes in normal mouse thyroid tissue after internal exposure to 211At.
A profound effect on gene expression in mouse thyroid tissue after 131I and 211At exposure was detected, and 27 genes, of which many are associated with immune response, were identified as potential biomarkers for 131I and 211At exposure, and the biomarker applicability of these genes should be further studied.
Among the 130 shared transcripts, 12/34 transcripts normally expressed in mouse thyroids and 31/96 transcripts for which gene expression has not yet been determined in normal mouse thyroid were down-regulated after exposure to 1.4 Gy but up-regulated after exposure to 0.05, 0.5, 11, and 32 Gy (Figure 2).
The fifth column shows the log2 values of gene expression in non-irradiated mouse thyroids (the present study).
Genes marked red are not expressed in normal mouse thyroid.
In addition, Dnase1 has detectable mRNA levels in mouse thyroid [29].
Genes categorized by known gene expression in mouse thyroid according to UniGene and The Human Protein Atlas.
The Human Protein Atlas and UniGene were used to establish normal expression of genes at the protein level in human thyroid and transcriptional level in mouse thyroid, respectively [23, 24].
Therefore, we identified normally expressed genes in normal mouse thyroid tissue by comparing mRNA expression levels for transcripts with previously known and unknown expression patterns in mouse thyroid [29].
