We next used RNA-seq to analyze the transcriptome of mouse testis affected by cadmium.
Lactate Dehydrogenase C Produces S-2-Hydroxyglutarate in Mouse Testis.
Guan, K. et al. Pluripotency of spermatogonial stem cells from adult mouse testis.
Kim, E. et al. Identification of novel retromer complexes in the mouse testis.
Kanatsu-Shinohara, M. et al. Generation of pluripotent stem cells from neonatal mouse testis.
Title Lactate Dehydrogenase C Produces S-2-Hydroxyglutarate in Mouse Testis.
Warr, N. et al. Gadd45γ and Map3k4 interactions regulate mouse testis determination via p38 MAPK-mediated control of Sry expression.
We measured DNA double-strand breaks (DNA DSBs) and oxidative stress parameters including malondialdehyde (MDA) content, superoxide dismutase (SOD) activity, and testis weight and sperm count at 12 h, 21 d and 35 d after irradiation in mouse testis.
In normal mouse testis, we found 70 μM S-2-hydroxyglutarate (2HG), more than 10-fold greater than in other tissues.
We report here the cloning and characterization of a novel cAMP-specific PDE from mouse testis.
