This scoring system revealed that both mouse and human metastatic populations exhibit higher stemness indices than non-metastatic populations, providing further evidence for a stem cell-driven component underlying the transformation to metastatic disease.
Microarray analysis of miRNA using The Mouse & Rat miRNA OneArray® v4 system revealed significant alterations in the expression of miRNAs in DIO and DIO + LFD mice.
Further analysis of this effect in the LabMaster system revealed that the reduction of BW, which in NPY−/− PYY−/− mice persisted for the whole observation period of 15 days, cannot conclusively be explained by alterations of activity and food intake.
Although they share two receptors, TACI and BCMA, transgenic and knockout mice in this system reveal that their functions are not redundant.
In conclusion, our model system reveals that complete repair of a myocardial infarction is possible in the newborn mouse.
Examination of peripheral organ systems reveals impaired ability of hematopoietic progenitor cells of PrPKO mice to colonize when transplanted to irradiated recipient mice [11], and poor recovery of PrP lacking animals from experimentally induced anemia [12].
It's an amazing cat and mouse system.
Studies in mouse model systems have revealed that hundreds of genes are involved in the host defense against microbial infections and that the interaction of these genes and pathways is very complex [27], [31] [37].
A previous study on the developing central nervous system in the mouse revealed a role for Reck in suppressing neuronal differentiation and expanding the neural precursor pool (Muraguchi et al., 2007).
