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The mouse system allowing the study of cell regeneration in response to chemical injury and more recently in vivo genetic lineage tracing [ 5, 6] has supplied a model to explore and describe epithelial lineages implicated in lung repair.
In summary, ENU mutagenesis of the haploid mouse ESC system allowed for a high level of saturation mutagenesis and recessive loss-of-function screening that would have been difficult to achieve in mammalian cells.
Here we show that postmortem microbial community changes are dramatic, measurable, and repeatable in a mouse model system, allowing PMI to be estimated within approximately 3 days over 48 days.
The use of the mouse model system allows us to develop predictive models that often cannot be derived directly from heterogeneous clinical sample data and could potentially facilitate exploration of the presence of a tumor-associated complex biomarker in mice prior to evidence of a tumor.
Cell cycling characteristics of the developing heart were analyzed using the FUCCI mouse system, which allows direct visualization of cell cycle phases in vivo (Sakaue-Sawano et al., 2008).
Thus our model system allowed us to study 4 distinct groups of mice that differed only in the presence of maternal and/or endogenous SIgA.
The whole system allowed it.
The use of this novel Cre-based virus/mouse system allowed identification of individual latently infected cells in vivo and may be useful for the study and long-term monitoring of other latent/persistent virus infections.
The whole system allowed it" (Skloot 2013 ).
A closed suction system allowed tracheobronchial aspiration.
Progresses on these topics are hampered by the lack of an in vitro culture system allowing mouse spermatogonia differentiation and entry into meiosis.
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CEO of Professional Science Editing for Scientists @ prosciediting.com