The brains of different mouse strains were collected from adult (4 month old mice) or newborn mice.
Some of these mutant mouse strains were found to exhibit behavioral abnormalities reminiscent of human psychiatric disorders.
Best to our knowledge, only inbred [49,51,53,58,59] but not outbred mouse strains were shown to display patient-like AKI alterations.
Methods: Seven inbred mouse strains were treated with CCl4, and hepatic fibrosis was phenotypically characterized by histology, hepatic hydroxyproline levels, and serum surrogate markers.
Two independent transgenic mouse strains were needed.
In addition, the mouse strains were compared pairwise in three separate PLS-DAs.
As shown in Figure 1A, two single transgenic mouse strains were generated.
Similarly, smLRP1−/−; LDLR−/− and smLRP1−/−; LDLR−/−; PDGFRβ F2/F2 mouse strains were established.
Two mouse strains were identified which exhibited a very pronounced susceptibility to influenza infections.
Seven mouse strains were tested in an established mouse model of chemical-induced asthma [8] [12].
Males and females from several mouse strains were used for the experiments.
