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The inbred mouse strains used in this study were Balb/c, C57BL/6, C3H/HeJ and DBA/1J.
Muscle, spleen and pancreas thymidine concentrations were measured in non-tumour-bearing mice in the PC and SCID mouse strains used at the CI (Fig. 3).
Phenotypic changes in brain and behavior of genetically modified mice can be masked or exacerbated by the genetic background of the mouse strains used.
Experts say the technique might find use as a cheap way to archive and transport the burgeoning number of mutant and transgenic mouse strains used in biomedical research.
Mouse strains used in this study have been described previously.
The mouse strains used in our study all carry a mutated Mx1 allele [55], except for FVB for which the status has currently not been characterized.
For the mouse strains used in our study, this locus accounts for 53% of the variance in survival observed in females and 62% in males.
M. avium infection in the mouse strains used in this study is controlled predominantly by the Nramp1 allelic variation, even in a highly polymorphic, segregating genetic setting [15].
A previous study reported no defect in lymphocyte numbers in IL-21R-deficient mice, which may be explained by the difference in mouse strains used compared to this study [31].
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First, we examined variations in the genomic landscapes of transposable repetitive elements, named the TREome, in conventional and genetically engineered mouse strains using murine leukemia virus-type endogenous retroviruses (MLV-ERVs) as a probe.
The individuality index was calculated for all mouse strains using data obtained at 5 day and daily sampling scales.
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