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Furthermore, as dexmedetomidine-induced sedation (as assessed by the Rotarod assay) and unstimulated LORR with dexmedetomidine are present in both the C57BL/6 and 129X1 mouse strains, this suggests that the α2A adrenergic receptors and associated signalling are working similarly.
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Additionally, for the antrum of both mice strains, this increase was never statistically significant (Figure 2F).
This unknown factor may compensate or over-compensate for the absence of myostatin to various degrees in different mouse strains, and this may ultimately affect cardiac size.
IIN values were calculated for pigs based on published data [24] and for all four mouse strains in this study (Table 1).
Expression of Nox 1 and 2 however, did not differ between these two mouse strains on this diet (figure 5b, 5c).
(Fig. 2 A ). BALF TGF-β increased further in WT but not HET mice at 6 d.p.i., resulting in no difference between mouse strains at this time point.
We acknowledge that there are variations in seizure sensitivity between different mouse strains, and this could ultimately impact the iDG phenotype.
C57BL/6JBomTac mice, purchased from Taconic (Denmark), were selected for the study as it is one of the mostly used mouse strains within this field due to its susceptibility to diet-induced obesity, type 2 diabetes, and low-grade inflammation [ 21].
Nevertheless, our results indicate that macrophages of only a few mouse strains express this paralog, and that there is no obvious correlation between macrophage sensitivity to LT and its expression.
Positional cloning using novel interval-specific congenic mouse strains narrowed this QTL to a 1.8-Mb interval with conserved colocalization of genes (i.e., shared synteny) on human chromosome 9p23 p22.3.
The inbred mouse strains used in this study were Balb/c, C57BL/6, C3H/HeJ and DBA/1J.
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