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In both mouse strains tested (C57Black/6 and NMRI), the measured infarct volumes decreased significantly during the first days after tpMCAO.
The same is true for the two AD mouse strains tested in the present study [4], [6].
However, BALB/c mice turned out to be limited producers of total serum IgE compared to the other mouse strains tested.
In summary, immunization with HIVBr18 was able to induce multiple T cell responses in all 4 HLA class II-transgenic mouse strains tested, against 16 out of the 18 epitopes encoded by the vaccine (Figure 4).
BALB/c mice showed the most pronounced differences in AHR, airway inflammation and immunologic parameters, when compared to the two other Th2-biased mouse strains tested (BP2 and A/J).
Thus, despite potentially playing an important role in the NK cell response to HCMV, in mice CD94-NKG2 receptors do not appear to be essential for the NK cell response to MCMV in the mouse strains tested, possibly due to redundancies in the NK response to MCMV.
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Different studies used different mouse strains, testing imprinting status in different tissues and developmental time points, and none of the studies published to date has employed a truly transcriptome-wide screen for imprinting.
Another by Pinter et al. [ 20] performed RNAseq in a reciprocal cross between two mouse strains, testing 7465 genes across two tissues and found 82 % of ASE genes showed TS ASE.
Induction of smooth endoplasmic reticulum, presumably including P450 induction, was present in the histology of all mice strains tested but was most prominent for Cbl-b /– male miCbl-b /
Groups of mouse strains were tested in three separate testing sessions over the course of two months, and all mice in a group were tested on the same day.
When several mouse strains are tested on highly standardized behavioral test batteries in different laboratories, significant strain×lab interactions are often detected.
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