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Conclusion: RT/PCR of lactating glands from ten different mouse strains revealed a message for a secreted form of Mgam, lacking the membrane binding coding exon.
The use of different mouse strains revealed that HVR5 substitution also led to dramatically less adenovirus liver transduction and associated toxicity, whereas HVR5-modified Ad were still able to transduce different cell lines efficiently, including primary hepatocytes.
Comparative genomic analysis of 129 and C57BL/6J mouse strains revealed indels and single nucleotide polymorphisms resulting in alternative or aberrant amino acid sequences in 1084 genes in the 129-strain genome.
Comparison of PAS-stained lungs between mouse strains revealed that regardless of the protocol used, OVA-sensitized and -challenged BALB/c mice had larger numbers of mucus-producing goblet cells than C57BL/6 animals.
In vivo studies using conditional knock-out mouse strains revealed that IL-10 production by T-cells, but not B-cells, was essential for the suppression of excessive gastric immunopathology.
A recent analysis of inbred mouse strains revealed that common laboratory strains have a significant, shared contribution from Mus musculus domesticus (Roberts et al. 2007; Yang et al. 2011).
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This technology has recently been used to characterize the genomes of some common inbred mouse strains, revealing extensive genetic variation between strains [ 13].
Bradford et al. (2011) measured variability in PK for TCE using a panel of inbred mouse strains, revealing marked differences among individual mice (e.g., a greater than 4-fold difference in peak serum concentrations of TCE metabolites).
Previous studies of this mouse strain revealed mainly altered immune responses, but no compensatory pathways and no CNS abnormalities have been reported.
Examination of this gene in the mutant mouse strain revealed that exons 10 to 14 had been deleted.
Using the same test setup, the initially highly anxious DBA mouse strain revealed a different exploratory strategy in comparison with the low-anxiety C57BL/6 strain, resulting in fewer memory errors over time (Ohl, Roedel, Binder, & Holsboer, 2003).
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