Sentence examples for mouse strains represent from inspiring English sources

Recent large-scale strain studies have shown that inbred mouse strains represent a diversity of physiological phenotypes similar to those found in human populations [21], [85].

It has been suggested that the organismal effects of SIRT6 deficiency, and similar metabolic phenotypes in other repair-deficient mouse strains, represent a homeostatic response to minimize ongoing genomic damage in the face of a DNA repair defect [ 34].

For example, the C57BL/6J (B6) and DBA/2J (D2) inbred mouse strains represent opposite ends of the spectrum with regard to voluntary oral consumption of alcohol, with B6 mice readily drinking large quantities and D2 mice consuming very little (e.g., Lê et al. 1994).

To identify novel C5-independent genetic effects regulating the proliferation of C. albicans organisms in target organs during disseminated infection, we surveyed 23 strains from the panel of 36 commonly used inbred mouse strains represented in the Jackson Mouse Phenome Database.

Therefore, the comparison of these two mouse strains represents a very suitable model system to identify genes that are associated with severe infection outcomes in humans [ 16].

B16 melanoma tumors in the C57/6J mouse strain represent one of the most commonly studied murine models for tumor immunotherapy.

Therefore, CXB mice strains represent a suitable model to fine map phenotypic effects associated with BALB/c-derived alleles, especially at the Papg1 locus.

Our knock-in mouse strain represents the first physiological animal model for autosomal dominant and recessive human desminopathies, as the expression of the mutant desmin is controlled by the endogenous gene regulation sites.

Two different mice strains representing different haplotypes, C3H/HeN (H-2k) and CB6F1 (H-2b and H-2d) were immunized 3 times with 5 µg of CTH1/CAF01 or rendered immune by prior i.n.n

Data for mice infected with strains representing each of the four F. tularensis subpopulations (A1a, A1b, A2 and type B) was previously published [ 16, 18].

The core phenotype data, including phenotype descriptions of each mouse mutant strain (represented as MP IDs) and Mammalian Phenotype Ontology (MPO), were retrieved from MGI.