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To identify genes required for remote memory, we screened randomly selected mouse strains harboring known mutations.
Crossing between mouse strains harboring various FGFRs mutations is extremely important to elucidate the interactions between different FGFRs.
As more divergent mouse strains, harboring even more cryptic SNPs, are used in studies, the impact of SNPs on interpreting results will become increasingly problematic.
Crossing mouse strains harboring different FGFs mutations with FGFRs mutant mouse models is necessary to discover the interactions between FGFs and FGFRs in skeleton development and homeostasis.
The finding that the respiratory chain capacity assessed in the presence of different substrate combinations was very similar in mouse strains harboring the short or long COX7a2l alleles was in stark contrast to the results from the Enriquez laboratory (Lapuente-Brun et al., 2013).
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Recently, it was reported that commonly used mouse strains harbor a short COX7a2l (SCAFI) gene isoform that supposedly precludes the formation of complex IV-containing supercomplexes.
Intriguingly, some nondiabetic mouse strains harbor a more diabetogenic allele than NOD mice for a given Idd locus (Brodnicki et al. 2003; Wang et al. 2014; Ghosh et al. 1993; McAleer et al. 1995).
An age-related shift toward higher thresholds for higher frequencies occurs in older mice (44) and, furthermore, the C57BL/6J and C57BL/6N mouse strains harbor a mutation in the Cdh23 gene that makes them more prone to age-associated hearing loss (44, 45).
Future experiments with GneD176V mice, a mouse strain harboring another mutation of GNE [48], could help us to determine whether different mutations of GNE all lead to an alteration of ST3Gal5 expression.
To dissect VNO function in controlling female reproductive and neuroendocrine status, we have developed a mutant mouse strain harboring a conditional, olfactory marker protein (OMP) and Cre-mediated ablation of Gαo [ 41].
CEA424/Tag is a transgenic C57BL/6 mouse strain harboring the Tag under the control of a -424/-8 bp CEA gene promoter which leads to the development of invasive adenocarcinoma in the glandular stomach.
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