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Open triangles – wild mouse strains; filled triangles – prion protein depleted; open circles – TG20; grey squares – C4; grey diamonds – line Harry.
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The deep, rich strains fill the room.
"Just a few yards from my office, there is an animal vivarium filled with hundreds of genetically altered mouse strains," he said.
All mouse strains were maintained on the C57BL/6 background.
It has lists of known mouse genes and reports of nomenclature committees on how to refer correctly to mouse strains.
& Mogil, J.S. Paclitaxel-induced neuropathic hypersensitivity in mice: responses in 10 inbred mouse strains.
"There are mouse strains that are infamous for this effect," Dr. Leibel said.
When cells from immunised mice are used in the fusion, the mouse × mouse hybrid myelomas can be grown as tumours in appropriate mouse strains.
There are two distinct developmental defects reported in global P38α knockout mice by two separate groups using different mouse strains.
Schmidt, E.F., Kus, L., Gong, S. & Heintz, N. BAC transgenic mice and the GENSAT database of engineered mouse strains.
Flacher, V. et al. Expression of langerin/CD207 reveals dendritic cell heterogeneity between inbred mouse strains.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com