Sentence examples for mouse strains derived from inspiring English sources
Genetically modified mouse strains derived from embryonic stem (ES) cells have become essential tools for functional genomics and biomedical research.
It's not unusual for toxicologists to work with outbred mouse strains derived from unrelated pairings.
Taken together our results suggest that strains specific pathogenesis may be due to a difference in the magnitude of the same pathways and/or to differentially expressed pathways in the two mouse strains derived macrophages.
For eight of these genes, human bacterial artificial chromosome clones were identified, retrofitted with a reporter, knocked single-copy into the Hprt locus in mouse embryonic stem cells, and mouse strains derived.
This analysis revealed shared and distinct expression profiles and showed that strains specific pathogenesis may be due to a difference in the magnitude of the same pathways but also to differentially expressed and potentially interconnected pathways in the two mouse strains derived macrophages.
Contrary to classical mouse inbred strains, where multiple subspecies contribute to the genetic make-up [ 13, 34] and recent mouse strains, derived from different Mus species [ 35], laboratory rat strains are most likely descending from a single rat species, Rattus norvegicus [ 10].
A spontaneous deletion resulted in a second mouse strain derived from the high-copy SOD1 G93A transgenic mouse.
Furthermore, we investigated whether, in a given mice strain derived macrophages, these coordinately regulated unique genes may be interconnected.
We next investigated whether, in a given mice strain derived macrophages, the different up-regulated unique genes could be coordinately regulated.
Taken together, our results show that the expression of these chemokines and some of their receptors is induced in both mice strain derived macrophages with however, a more rapid and heightened expression in C57BL/6 BMdMs.
Figure 3 presents an alignment of all ZFA diagrams of wild-captured mice, inbred strains derived from wild mice, and commonly used laboratory inbred strains.
