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However, the ability of this mouse strain to heal isolated cutaneous wounds by regeneration or with scar is unknown.
To test this, we performed lineage tracing experiments using the recently developed tamoxifen-inducible Cre at Axin2 mouse strain to follow the developmental fate of Wnt/β-catenin-responsive cells in both the embryonic and postnatal mouse brain.
It is not possible, based on the study design employed, to determine the underlying basis for the apparent resistance exhibited by this mouse strain to CSC-induced tumor promotion.
To their surprise, many of the cells failed to form teratomas at all similar to what the researchers saw when they transplanted ES cells from one mouse strain to another.
This mouse strain has a deletion of the TLR4 locus, causing the mouse strain to be nonresponsive to stimulation by LPS from Escherichia coli while responding normally to other bacterial substrates, such as lipoteichoic acid (LTA) from Staphylococcus aureus, which signal TLR4 independently.
We chose to perform the methacholine provocation with the same methacholine concentrations for each mouse strain to make comparisons easier.
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The French first tested a series of laboratory mouse strains to find a genetic type that was most likely to die after being exposed to the West Nile virus.
We typically use basic molecular and cellular approaches and apply our findings to complex genetic systems (compound mutant mouse strains) to study blood vessel structure and function in physiology and disease.
We combined molecular and aCGH analyses of CNVs in inbred mouse strains to investigate this question.
We are also thankful to J. Lewis for providing the floxed Jag1 and Dll1 mouse strains, to R. Klein for Nestin-Cre strand and to N. Kessaris for Rosa26-YFP mouse strain.
We have used a representative panel of 23 phylogenetically distant inbred mouse strains to study the genetic control of susceptibility to acute and disseminated C. albicans infection.
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