We previously demonstrated that an attenuated strain of Salmonella enterica serovar Typhimurium, engineered to express IL-2 (strain GIDIL2), is cleared more rapidly than its parental, non-cytokine-expressing, strain (designated BRD509) from the reticuloendothelial system of susceptible BALB/c mice.
The strain, designated "GII.4 Sydney," appeared in Australia last March.
This strain, designated PHDC, lacks both B cepacia epidemic strain and cblA markers.
One strain, designated FM145, was selected for intensive further scrutiny.
The strain, designated YN, was genetically and pathologically characterized.
This strain was considered to be a susceptible strain (designated ACB-BtS).
Many strains of T. gondii (e.g., the abundant Eurasian strains designated types II and III) are well controlled by the IRG system in laboratory mice, encyst, and are considered avirulent.
Within GIII, four different strains, designated A D, were detected.
GTM fingerprints from replicate (n = 3 6) animals, housed at the University of Manchester (designated environment A) clustered together, based on mouse strain with inter-strain concordance, ranging from 71 to 100% and intra-strain concordance between 50 and 55% (Fig. 1).
To gain a better understanding of β-Trcp redundancy, Kanarek et al. recently generated a mouse strain with inducible β-Trcp2 knockdown in combination with β-Trcp1 KO (designated as KO1/KD2).
