Sentence examples for mouse strain containing from inspiring English sources

An in vivo interaction between Myb and p300 was revealed by the identification of the plt6 mouse strain containing a mutation in the KIX domain.

An E14Tg2a.4 ES cell line (derived from the 129/OlaHsd mouse strain) containing a gene-trap cassette inserted into the Prkd2 locus (RRJ380, Bay Genomics) was injected into C57Bl/6J blastocysts, which were subsequently implanted into recipient female mice.

We applied a proteomic approach to a mouse strain containing a null mutation of the Ugt1 gene with the aim of shedding light on the mechanisms and molecular effectors involved in bilirubin-associated neurotoxicity in vivo.

To distinguish the functions of secreted BMP2 from nBMP2, we generated a mouse strain containing a targeted mutation in which the conventional growth factor BMP2 is secreted and signals normally, but nBMP2 is excluded from the nucleus by means of a three-amino-acid substitution in the nuclear localization signal [ 2].

The targeting vector used to create the Lrp6−/− mouse strain contained the β-galactosidase (β-gal) gene.

We have also found that some common mouse strains contain a natural mutation in Bfsp2 that will effectively generate a CP49 knockout.

None of the three generated double knockout mouse strains contained the rd8 mutation or presented signs of the early onset AMD-like features previously described (Tuo et al, 2007).

To gain insight into the signal transduction events mediating this response we compared the properties of the P2X7R Panx1 complex in astrocytes from a mouse strain (C57Bl/6) containing a naturally occurring point mutation (P451L) in the C-terminus of the P2X7R to that of non-mutated receptors (Balb/C mice).

To do so, heterozygous matings were carried out among the above ATEflox/+ mice, the previously constructed ATE+/− mice [10], and a mouse strain that contained the CaggCreER gene, expressed from the ubiquitously active chimeric Cagg promoter [25].

Henceforth, we studied the role of SARM 724 in T cells using transgenic OTI+RAG−/− mouse strain, which contains homogenous populations of cytotoxic T cells (Supplementary Figure S1e) and a B6.PL-Thy1a/CyJ moustrainain, which expresses the congenic Thy1.1 marker.

The transgenic mouse platform employed includes several mouse strains, each containing DNA encoding parts of the human variable region antibody repertoire and varying human constant regions.