Sentence examples for mouse skin induced from inspiring English sources
Transgenic expression of active MEK1 in mouse skin induced hyperplasia, hyperkeratosis and perturbed differentiation of the epidermis [ 15, 16].
By contrast, similar treatment with Fraction N QG), a fraction having very low tumorigenic activity for mouse skin, induced no SqN and barely any excess of SqM over that induced by either vehicle alone.
Evidence for chemical promotion or cocarcinogenesis was first provided by Berenblum, who reported that a regimen of croton oil (weak or noncarcinogenic) applied alternately with small doses of benzo(a pyrene (BP) to mouse skin induced a larger number of tumors than BP alone.
Daily application of the TLR7/8 agonist imiquimod cream (Aldara®) on mouse back skin induces skin inflammation that strongly resembles human psoriasis in terms of phenotypic and histological features [22].
Moreover, they had the strongest effect on reduction of cyclooxygenase-2 levels in mouse skin inflammation induced by ultraviolet B (UVB) light.
Primary fibroblasts [28] were isolated from mouse skin tumor induced by two stage carcinogenesis regimen and characterized as tumor-associated fibroblast (TAF) [28], [31].
We show that, from the earliest morphologically recognisable stages of development, mouse skin papillomas induced by a chemical initiation-promotion regime are polyclonal.
The role of TPA-S1 in tumor promotion is suggested by the expression of this sequence in mouse skin carcinomas induced by dimethyl-benzanthracene-TPA treatment, but not in papillomas or in control tissue.
Beta-propiolactone-induced rat nasal carcinomas contain a novel oncogene, 6 to 9 kb in size, whereas a mouse skin carcinoma induced by this agent possesses an H-ras oncogene activated by a 61st codon A to T transversion mutation.
15 Isoflavones have been shown to help inhibit the aging of skin induced by UV light in mice, and photodamage caused to skin, and attendant discomfort, in humans.
Kakar and Roy [ 15] demonstrated that topical application of curcumin on mouse skin inhibited TPA induced expression of c-fos, c-jun and c-myc oncogene.
