Sentence examples for mouse sickle cells from inspiring English sources

The deoxygenation-activated conductance in SAD mouse sickle cells was reversible upon re-oxygenation.

Several of these properties shared by human and mouse sickle cells are consistent with those of Psickle.

We have also demonstrated by fluorimetry deoxygenation-activated elevation of [Ca2+]i in single human SS red cells and mouse sickle cells.

The deoxygenation-activated conductance is likely responsible for [Ca2+]i elevation in human and mouse sickle cells, leading to activation of KCa3.1 (Gardos channel), with consequent acceleration of pathological sickle cell dehydration.

The conductance induced by deoxygenation in on-cell patches of human HbSS red cells and of mouse sickle cells is permeable to Na+, to Ca2+, and to other cytoplasmic cations.

These observations extend the phenotypic characterization of deoxygenation-activated Ca2+ transport in human sickle red cells, and present the first such data in mouse sickle red cells.

Skin cells from a mouse with sickle cell anemia can be genetically reprogrammed to be pluripotent stem cells, then differentiated and used to treat the diseased mouse.

When the DNA was inserted via HIV-based vectors into stem cells from two strains of mice with sickle cell disorders, 99% of the red blood cells in the mice expressed the protective gene for up to 10 months, with no signs of sickling.

Mouse iPS cells could differentiate into hematopoietic precursor cells that have been used to rescue the mice with sickle cell diseases [ 18].

Ghosh, S., Tan, F. & Ofori-Acquah, S. F. Spatiotemporal dysfunction of the vascular permeability barrier in transgenic mice with sickle cell disease.

By forcing adult mice with sickle cell disease to produce a fetal version of the hemoglobin molecule that carries oxygen in blood, a research team has eliminated symptoms of disorder in the animals.