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Immunohistochemical analysis of the skeletal muscle of the adult mouse revealed a dot-like staining pattern of the antibody in transverse sections and a striated staining pattern in longitudinal sections.
Here, genetic analysis of coincident loss of Pten and Ink4a/Arf tumor suppressors in the mouse revealed a neoplastic phenotype dominated by a premalignant expansion of biphenotypic myelolymphoid cells followed by the development of HS.
In contrast to the present results, our previous study of the SERT KO mouse revealed a generally more robust cortico-limbic circuit compared to WT mice.
Histological evaluation of tumors in each mouse revealed a macroscopic tumor and microscopic tumor foci in mouse i and ii respectively (Fig. 5c).
Stronger contrast was achieved by reflecting the scalp (TNR = 3.7±1.1) and further removal of the skull of the mouse revealed a highest TNR of 4.2±1.1 (Fig. 4C).
Our extensive immunofluorescence analysis (using antibodies against specific histone modifications) in nuclei of mammals distantly related to human and mouse, revealed a general absence from the mammalian Xi territory of transcription machinery and histone modifications associated with active chromatin.
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Experiments with the engineered mouse reveal a molecular mechanism by which mutations of the gene named Shank3 affect the brain and behavior to evoke an autismlike disorder in mice.
The analysis of a GCAP1 and GCAP2 double-knockout mouse reveals a photoresponse with larger amplitude and delayed decline compared with the wild type (Mendez et al., 2001).
Histological analysis of Sgca null:Mlc1f-Nfix2 mice revealed a markedly worsened phenotype with respect to Sgca null mice, both at 5 (Fig. 5a) and 8 weeks (Fig. 5b).
To this end, recent experiments on transgenic Alzheimer mice revealed a progressive regression of the neurodegenerative disease after controlled exposure to mobile phone radiations.
The selective DOCK8-deficiency in Tregs of FOXP3YFP Cre/Dock8flox/flox mice revealed a higher risk to develop autoimmunity37, pointing to an important role of DOCK8 function in Tregs for maintaining self-tolerance.
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