Sentence examples for mouse retinal progenitor from inspiring English sources

In this study, we engineered and analyzed a micro-fabricated polymer, poly(glycerol sebacate) (PGS) scaffold, whose useful properties include biocompatibility, elasticity, porosity, and a microtopology conducive to mouse retinal progenitor cell (mRPC) differentiation.

Our data suggest that Rb and p107 share the same role in regulating mouse retinal progenitor cell proliferation but the role of Rb is unique in rods.

It has been shown previously that RNAi-mediated knockdown of Meis2 in chick and mouse retinal progenitor cells inhibits cell proliferation, suggesting that Meis2 is essential for maintaining the progenitor cells in a rapidly proliferating state.

Of the vision related genes highly biased in M. davidii IKZF1 encodes a transcription factor called Ikaros family zinc finger 1, an ortholog of which confers competence to mouse retinal progenitor cells (Elliott et al. 2008).

Following the pioneering work by Watanabe and colleagues on telencephalic specification (Watanabe et al., 2005), Ikeda and colleagues used antagonists of the nodal (LeftyA) and Wnt (DKK-1) pathways in addition to activin-A and serum to derive mouse retinal progenitor cells (Rx+/Pax6+) after 10 days of differentiation.

One possible explanation for the lack of compensation in the human retina is that the p107 promoter is sequestered in an inactive chromatin conformation in human fetal retina, but it is in an active chromatin conformation in mouse retinal progenitor cells and is thus poised to respond to a loss of Rb.

The formation of the optic vesicle in teleosts is qualitatively different from that in mouse and chick embryos; for instance, instead of evaginating as in the mouse, fish retinal progenitor cells individually migrate out laterally from the neural tube and form a vesicle by local epithelialization [ 16].

69 In the Pax6-knockout mouse retina, the retinal progenitor cells become totally restricted to an amacrine cell fate.

In contrast to mice, human fetal retinal progenitor cells primarily express RB1 during development.

The primary Rb family member expressed in proliferating embryonic retinal progenitor cells in mice is p107, which is required for appropriate cell cycle exit during retinogenesis.

We report here that in the developing mouse retina p107 is expressed in embryonic retinal progenitor cells, and Rb is expressed in postnatal retinal progenitor cells.