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To this end, the clearance of the alveolar Gaucher cells in the 9 V/null mouse receiving a potent GC synthase inhibitor Genz 112638, i.e., substrate synthesis inhibition therapy, has been observed [47].
The mice were inoculated intraperitoneally with 0.2 ml PBS suspension of C. burnetii (grown in BGM cell culture) with each mouse receiving a dose of 10 genome copy equivalents as determined by quantitative PCR [ 20].
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Each mouse received a total of ∼3×107 cfu.
Each mouse received a subcutaneous (s.c).
A 'donor mouse' received a subcutaneous tumour cell implantation.
Each mouse received a single intraperitoneal (IP) injection of drug as indicated.
Each mouse received a preoperative subcutaneous injection of 1.5 mg oxytretracycline and 0.003 mg of buprenorphine.
Once crossed into the dark chamber, the mouse received a 3-s 0.45-mA footshock.
In mice receiving a control adenovirus no citrullinated proteins were observed.
Thus, mice receiving a high dose of DOX alone lost significantly more weight over time in contrast to mice receiving a lower non-effective dose of DOX alone (0.05 mg/kg), or mice receiving APMS-MB-DOX (0.05 mg/kg).
Each mouse received an accurate 0.1 mL of the emulsion each time.
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