For decades, space powers have lofted ants, spiders, mice, rats, frogs, snails, fish, turtles, guinea pigs, cats, dogs, monkeys and chimpanzees as cover stories for military programs and as high-flying experiments meant to pave the way for sending humans into orbit.
We therefore undertook an analysis of the human genomic regions confined by consecutive HCE pairs common to eight genomes (human, mouse, rat, chicken, frog, zebrafish, tetradon and fugu).
To investigate evolutionary conservation of the 33 novel chicken miRNAs, a search for highly similar sequences among human, mouse, rat, opossum, frog and zebrafish genomic sequences was carried out using a BLAST analysis.
We have therefore integrated the three datasets [ 1- 3] and undertaken an analysis of the human genomic regions confined by HCE pairs common to eight genomes (human, mouse, rat, chicken, frog, zebrafish, tetradon and fugu).
We used BLASTn with non-stringent parameters and criteria for order and genomic distance conservation to locate all occurrences of the same HCEs in the mouse, rat, chicken, frog, zebrafish, fugu and tetraodon genomes [see details in Methods; Additional file 2].
ChIPseek supports 20 different genome assemblies for 12 model organisms including human, mouse, rat, worm, fly, frog, zebrafish, chicken, yeast, fission yeast, Arabidopsis, and rice.
We also compare human, mouse, rat, rabbit, chicken, frog, and zebrafish PXRs with a set of common compounds that activate most PXRs.
We performed protein function predictions using the FALCON algorithm on the unannotated parts of the genomes of 6 eukaryotes (human, mouse, rat, slime mold, frog and arabidopsis).
Orthologs of TERT have been identified in many vertebrates including human, dog, mouse, rat, hamster, chicken, frog (Xenopus laevis), and several fish (Danio rerio Takifugu rubripes Nothobranchius furzeri, Oryzias latipes, O. melastigma, and Epinephelus coioides) [ 22, 39- 48].
Alignment of protein sequences revealed that the alanine (A436) and aspartic acid (D448) residues found to vary in NTD patients are highly conserved (in human, chimpanzee, macaque, mouse, rat, dog, chick, frog, and zebra fish).
