Sentence examples for mouse plasma cell from inspiring English sources

We generated a mouse plasma cell tissue culture (PCT-TC) gene signature by comparing and contrasting the global gene expression of solid mouse plasma cell tumors with that of plasma cell tumors adapted to grow in tissue culture.

In summary, we generated a novel prognosis prediction model for human breast cancer patients based on a mouse plasma cell tumor tissue culture expression signature.

Our model was developed using genes differentially expressed in mouse plasma cell tumors growing in vivo versus those growing in vitro.

Thus, we undertook the comparison of gene expression profiles between mouse plasma cell tumors (PCTs) growing in mice and PCTs that had been adapted to growth in tissue culture, hoping to gain insights into the genes responsible for the adaptation of this particular tumor to tissue culture conditions.

Unlike human myelomas, mouse plasma cell tumors have a common initiating event, a Myc-activating chromosome translocation.

In 1965, Tom and Max Whisson reported the regression and cure of established ADJ-PC5 mouse plasma cell tumours by a single dose of aniline mustard (IX; Connors and Whisson, 1965a, 1965b).

qPCR analyses of sorted mouse plasma cells and B220+ splenic B cells revealed that transcript levels for Eef1a2 were below the levels of detection in both populations (data not shown), an observation consistent with earlier studies showing that EEF1A2 is normally expressed only in heart, muscle and brain.

Our observations fit well with previous studies demonstrating human and mouse plasma cells in blood 7 to 10 days after immunisation [17], [63], [64], and support the idea that this transient appearance of PC in blood represents the normal migration of PC after antigen stimulation and B cell differentiation.

We have established TS-jPCR and used it for the rapid production of recombinant monoclonal antibodies from mouse plasma cells.

Starting from fifty-three isolated mouse plasma cells, we achieved amplification of the VH and VL genes within a single day.

DNA fragments of the VH and VL chain genes from single mouse plasma cells were amplified by the rapid amplification of the 5' cDNA ends by polymerase chain reaction (5' RACE-PCR) [ 16].