Sentence examples for mouse phenotype with from inspiring English sources

Briefly, the associations of a mouse phenotype with SNP markers on the genome were tested by using linear regression models.

In summary, we have described the mouse phenotype with genetic loss of the multifunctional transcriptional repressor SAFB2.

However, a direct comparison of the mouse phenotype with the human disease is limited by the anatomical differences between murine and human skin.

We have now performed a detailed analysis of the Dnmt2 mutant mouse phenotype with a specific focus on the haematopoietic system as a paradigm for cellular proliferation and differentiation.

3) It might be worth pointing out that type I strains are relatively rare, yet they share the "acute lab mouse" phenotype with many South American strains that not coincidentally share a ROP18 allele (and also ROP5 although this is less well characterized).

We identified strong differences among mouse phenotypes with respect to the immune-associated gene expression patterns characteristic of human psoriasis, with the K14-AREG, K5-Stat3C and K5-TGFβ1 phexhibitingxhibiting a closer correspondences to human psoriasis (Figure 8).

The approach used in this study to evaluate psoriasis mouse models represents a general strategy that can be applied to score alternative mouse phenotypes with resemblance to specific human diseases.

Taken together, these analyses support a ranking of mouse phenotypes with regard to overall inflammation intensity, with the strongest inflammation signature in K14-AREG lesions, moderately strong inflammation in K5-Stat3C and K5-TGFβ1 lesions, weak-to-moderate inflammation in K5-Tie2 lesions, and weak inflammation in the phenotype generated by topical application of IMQ.

Comparisons of mouse phenotypes with clinical descriptions will facilitate a better understanding of the genetic component of vertebral malformations.

Kwon and Sevick-Muraca [ 13] reported an exciting approach that uses near-infrared fluorescence to nondestructively and quantitatively image the lymphatic system and its contractile function for mouse phenotyping, with the help of injecting indocyanine green in normal and transgenic mice.

ToppGene combines mouse phenotype data with human gene annotations and literature.