Sentence examples for mouse phenotype developed from inspiring English sources

Interestingly, BH3 mutant transgenic mice, in contrast to the reported wild-type Bcl2 transgenic mouse phenotype, developed multi-organ autoimmune pathology and died around one year-of-age.

However in γ-synuclein transgenic mice, the pathological phenotype develops much earlier and is substantially more severe.

Here we tapped the rich resource of mouse phenotype data and developed a method to quantify the probability that a gene perturbation causes the phenotypes of a disease.

Thus, a robust polycythemic phenotype develops in splenectomized mice in response to wild type (Epo→Epo receptor→Jak2) signaling.

Following pIpC treatment of adult mice, heterozygous mice developed a PV-like phenotype, including markedly increased haemoglobin, haematocrit, red blood cells, leukocytosis, thrombocytosis, splenomegaly, reduced serum erythropoietin (Epo) levels and Epo-independent erythroid colonies.

These were developed from the mouse phenotype table of genes with mouse phenotype ontological codes ftp://ftp.informatics.jax.org/pub/reports/index.html pheno, downloaded on 4-4-08 4-4-08 4-4-08

For example, mice carrying a human disease mutation without developing a corresponding mouse phenotype invalidate the use of that transgenic "model" to study potential therapeutics, because there is no pathology that the therapeutics could act upon.

This mouse model developed ALS-like phenotype and pathology.