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Previous work on CI-1040 halreadyady established that this drug has a cytostatic effect on subcutaneously implanted colon tumors of human and mouse origin harboring RAS mutations [ 21].
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Similar with the present finding, Mekuria et al. (2014) showed that 23.7% samples from food of bovine origin harbored E. coli.
The breeding of SirT1co/co mice and CMV-Cre transgenic mice results in mice harboring a germline-transmitted deletion of exon 4 of the SirT1 gene (SirT1+/ko mice).
SirT1+/ko, Cre+ mice were backcrossed with wild-type mice to generate the mice harboring a germline-transmitted deletion mutation (that is, SirT1+/ko mice).
However, these approaches have only been demonstrated in human tumor-derived cell lines or mouse models harboring mtDNA mutations.
A mouse model harboring embryonic deletion of Sav1, Mst1/2 or Lats2 in the heart revealed the importance of these Hippo components for proper organ development [60].
To identify genes required for remote memory, we screened randomly selected mouse strains harboring known mutations.
Mouse models harboring these human mutations were generated but fail to fully recapitulate human AD.
Millions of Americans, regardless of their skin color, religion, ethnicity, or national origin, harbor varying degrees of distrust of people who are "not like us".
Smyd2fl/fl mice were mated with Smyd2wt/fl mice harboring the Nkx2 5/Cre transgene (Smyd2wt/flCre) to obtain Smyd2 conditional knockout (cKO) mice (Smyd2fl/flCre).
First, we infected primary mouse fibroblasts (MEFs) harboring a miR-17∼92 miR-17∼92[32].
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