Sentence examples for mouse neuron development from inspiring English sources
Reports regarding the function of DYNLT1 have focused on the role of this gene in mouse neuron development [32] and have included observations of direct interaction of this protein with specific neuronal Ca2+ channels in rats [33].
Two recent mouse studies revealed an indispensable role of Rnd3 in mouse neuron development.
The best characterized functions of RND3 are its inhibitory effect on Rho kinase-mediated biological functions including actin cytoskeleton formation, phosphorylation of myosin light chain phosphatase, and apoptosis 6– 8. Two recent mouse studies revealed an indispensable role of RND3 in mouse neuron development 9, 10.
APP null mice have retarded neuron development, reduced hippocampal neuron viability, diminished grip strength, locomotor activity and postnatal growth [7], but can be normalized by over expression of the sAPP-α ectodomain [8].
To assess whether NRP1 plays a role in GnRH neuron development, we studied mice carrying the Nrp1-null mutation on a genetic background (JF1) that allows homozygous null mutants to survive the early phase of cardiovascular development (Schwarz et al., 2004).
Foxp1 has also previously been shown to promote mDA neuron development during the differentiation of mouse ESCs (Konstantoulas et al., 2010).
Transgenic mouse dams with a specific disruption in 5-HT neuron development display profound maternal deficits (Lerch-Haner et al. 2008).
To investigate the potential role of GDF5 in hippocampal neuron development, we established dissociated cultures from mouse hippocampi at E18, a stage at which the predominant neuron type is the pyramidal cell.
In order to further characterize the function of Dkk1 in midbrain DA neuron development we analyzed the few E17.5 Dkk1−/− mice that we obtained.
We also studied GnRH neurons in the hypothalamus of embryonic and adult Chd7 Whi /+ mice and analysed the expression of Chd7 during olfactory and GnRH neuron development.
This effect on genes involved in neuron development confirms earlier reports of Alzheimer-like effects in mice infected with H5N1 [ 36] and possible association with Parkinsonism [ 37].
