Sentence examples for mouse mutants we from inspiring English sources
Using the ODD-luciferase transgenic mouse in concert with tumorigenic mouse mutants, we have analyzed base-line background signals from non-tumor-bearing mice, imaged a series of spontaneously developing mammary tumors over time, and conducted a proof-of principle study showing the feasibility of this model.
Following a screen for neuromuscular mouse mutants, we identified ostes, a novel N-ethyl N-nitrosourea-induced mouse mutant with muscle atrophy.
To investigate possible alterations in the lipid profiles of the Pcdh15 mouse mutants, we measured the lipid levels of two mouse mutants homozygous for different loss of function mutation in Pcdh15 (Pcdh15av-Tg and Pcdh15av-3J) (Fig. 3a).
In contrast to almost all published Scn8a mouse mutants, we did not observe degenerative changes in skeletal muscle, cerebellum or any gait defects or paralysis in Scn8a Clth /Scn8a Clth mice.
Using histology, molecular markers and analysis of Celsr1 and Vangl2 mouse mutants, we conclude that though both are obligatory for normal lung development, these proteins regulate some distinct steps in airway formation.
This information is crucial for the analysis of a mouse model for cystinosis which, in the absence of a spontaneous mouse mutant, we are currently generating in order to study the pathogenesis of cystinosis in vivo.
In the aneuploidy (XY* model) mouse mutant, we measured Gh mRNA in mPOA and found a significant positive relationship between levels of Gh and numbers of X chromosomes [ 9].
It was through analysis of the most severe ciliogenesis mouse mutants that we gained initial insight into the molecular roles of cilia.
Here, we report a new ENU-induced mouse mutant that we have named hitchhiker (hhkr), which exhibits a range of developmental abnormalities including neural tube defects and polydactyly.
In summary, Tex19.1−/− mouse mutant that we generated confirms the spermatogenic phenotypes of a previously reported Tex19.1 mutant [15].
Using the Atmin mouse mutant Gasping6 (Gpg6), we investigated kidney development and found it severely disrupted with reduced branching morphogenesis, resulting in fewer epithelial structures being formed.
