Sentence examples for mouse mutants such from inspiring English sources
Third, the deletion mice were able to maintain their core body temperature in a 4°C environment, in contrast to many obese mouse mutants, such as ob/ob, db/db (null for leptin receptor), and stat3-/ mice, that quickly become hypothermic in the cold [24], [45].
Such a phenotype is also seen in other mouse mutants, such as the pirouette/GRXCR1 mutant.
Small body size is a striking characteristic of most long-lived mouse mutants such as the Ames Dwarf, Snell Dwarf and Little mouse (reviewed in Bartke, 2005).
With the limitations and complexities surrounding retrospective human studies (6), the analysis of mouse mutants such as Bdr subjected to environmental manipulation will become an increasingly important tool for the study of neuropsychiatric disorders.
Consistent with this, all mouse mutants lacking otoconia (such as tilted, head slant, and head tilt mice) have severe balance deficits [20], [21], [22], [23].
Comparing to ApcMin mice, despite the significant increase in polyps in the small intestine, there is no increase in polyps in the colon in mice with some Apc mutants, such as ApcΔ716.
The loss-of-function type mouse mutants of Gsdm family genes, such as the Gsdmd KO mice in our previous study and the Gsdma KO mice in this study, show neither morphologic anomaly such as epithelial hyperplasia nor tumor development (Fujii et al. 2008).
Our experimental approach using conditional knockout mice presents more advantages than global mutants such as IL-6−/− in which the effect of changes in tumor growth cannot be attributed to a specific cell-type.
There is also soft tissue syndactyly, which is common in mutants such as Prickle1-/ mice.
Such features resemble the phenotypes of Alx4 Lst/Lst mouse mutants.
She recognised the advantages to biomedical science of cryopreservation of mouse mutants and strains; and the archive of frozen mouse embryos at Harwell, which provides such an important repository for biomedical science worldwide, is testament to her foresight.
