Sentence examples for mouse mutants including from inspiring English sources

There are a multitude of Alms1 mouse mutants, including ENU mutants, gene-trapped alleles and spontaneous mutations (Table 2).

To investigate the roles of different GFRa co-receptors further, Fleming, Vysochan et al. generated a variety of mouse mutants, including mice with mutations in one or both types of co-receptor.

The pathogenesis of OM is multifactorial in mouse mutants, including defects in host defence (43– 45) and the mucociliary system of the mucosa lining the middle ear cavity (46– 46).

Perinatal lethality has been described for several FA mouse mutants, including Fancc (Carreau, 2004), Fancd2 (Houghtaling et al., 2003; van de Vrugt et al., 2009), Fancl Agoulnikk et al., 2002), Fancm (Bakker et al., 2009) and Fancp (Crossan et al., 2011); however, the mechanism for this lethality has not been studied.

To examine the role of the N-terminus of DGAT1, we prepared two mouse DGAT1 truncation mutants including a fragment consisting of amino acids (aa) 1 95 and the other consisting of aa 95 498 according to the ClustalX2 result.

We used four different types of wild-type controls and mutants including Pcd mice, L7-Pp2b mice, L7-Δγ2 mice and α6-Cacna1a mice, all of which had a C57BL/6 background.

All three are features of the long-lived, slow-aging GHR-KO mouse, and overlap features of other slow-senescing mutants, including dietarily restricted mice.

I've always been very happy to provide mouse mutants to other people – including my competitors.

Furthermore, Scn8a Clth /Scn8a Clth mice displayed a greater frequency of trunk curling and limb grasping, which are often displayed by mouse mutants with neurological defects including Scn8a med − TgA 4 Bs / Scn8a med − TgA 4 Bs mice (Kohrman et al. 1995).

These mice display other features found in BRCA2 mutant mice, including germ-cell defects, small size, and perinatal lethality [ 11].

The authors noticed that the reported phenotype of mice lacking the epithelial-specific FGFR2b isoform was remarkably similar to that of their p63 mutant mice, including cleft palate and a strongly hypo-plastic and hypo-proliferative skin (Rice et al, 2004).