Sentence examples for mouse mutant with from inspiring English sources

Here, we report the identification of a hyperactive N-ethyl-N-nitrosourea (ENU -induced mousENU -inducedh abnormouseies in the lamutantarchitecture of the hippocampus and cortex, accompanied by impaired neuronal migration.

A transgenic mouse mutant with reduced Dkk1 expression displays postnatal polysyndactyly, which can be partially rescued by the concomitantly reduced expression of Lrp5/6 [41].

To test the possible role of Rad1K185 modifications in controlling mammalian DDT, we generated a mouse mutant with a site-specific Rad1K185R mutation in exon 4 of the Rad1 locus (Figure 1A).

An ENU mouse mutant with increased CD44hi cellsells and anti-nuclear autoantibodies.

Of the 59 genes, 26 represent the first mouse mutant with publicly available data.

A mouse mutant with uncleavable PKD1 exhibits abnormal kidney development (Yu et al, 2007).

Since numerous new mouse mutants with a hair phenotype have been reported since the publication of our earlier review on this matter a decade ago, we present here an updated, tabulated mini-review.

Because many basic and clinical studies suggest that alterations of the hypothalamic pituitary adrenocortical (HPA) system are involved in the development and course of depression, mouse mutants with genetic modifications of genes regulating the HPA system were generated.

Second, intercellular cholesterol transport in the CNS is perturbed in patients with MS, because of reduced abundance of relevant proteins such as ApoE (Apolipoprotein E 10; and in mouse mutants with BBB disruption22, by uncontrolled flux of sterols in and out of the brain.

This overview should provide helpful pointers to investigators who are looking for mouse models to explore or to compare functional activities of genes of interest and for comparing coat color phenotypes of spontaneous or genetically engineered mouse mutants with novel ones.

The updated annotated tables list a wide selection of mouse mutants with hair growth abnormalities, classified into four categories: Mutations that affect hair follicle (1) morphogenesis, (2) cycling, (3) structure, and (4) mutations that induce extrafollicular events (for example immune system defects) resulting in secondary hair growth abnormalities.