Sentence examples for mouse mutant uncovered from inspiring English sources

A hypomorphic ATF2 mouse mutant uncovered a variety of developmental abnormalities, leading to defects in endochondral ossification as well as defects in the nervous system.

It further emphasizes the value of extensive phenotyping tests on mouse mutants to uncover new mutant phenotypes [23].

Studies using these mutant mice uncovered that FGFs/FGFR1 signals may regulate intramembranous bone formation.

For each of these inherited disorders, a genetically defined mouse mutant can help identify the key molecular defects in excitability and plasticity in the developing epileptic brain, uncover new molecular targets for therapy, and serve as a reproducible biological test system for experimental strategies to prevent or reverse the onset of seizures.

In this study, we employed S89G-DMP1 micentomice to uncover the function of DMP1-PG during astrocytes maturation and maintenance of BBB integrity.

Further characterization of Bcl11a mutant mice also uncovers the key role of Bcl11a in the fetal to adult expression switch of hemoglobin [ 109].

Mouse mutants will be informative to reveal the general importance of Krm1/2 for Dkk action.

Seibler, J. et al. Rapid generation of inducible mouse mutants.

Yoon, K. & Gaiano, N. Notch signaling in the mammalian central nervous system: insights from mouse mutants.

Herrmann, S., Hofmann, F., Stieber, J. & Ludwig, A. HCN channels in the heart: lessons from mouse mutants.

Here, by analysing several models of transcriptional adaptation in zebrafish and mouse, we uncover a requirement for mutant mRNA degradation.