Sentence examples for mouse mutant in from inspiring English sources

Here, we report a mouse mutant in which the piggyBac (PB) transposon is inserted into the Lmod3 gene and disrupts its expression.

Results In the present study, the authors describe a mouse mutant in which the piggyBac (PB ) transposon is inserted into the Lmod3 gene to disrupt its expression.

Here, we describe a mouse mutant in which the homologous Lmod3 gene on mouse chromosome 6 is disrupted by a piggyBac (PB) transposon insertion.

Together, these data support the argument that pulmonary defects can result from cilia dysfunction; we were therefore intrigued by the reported lung phenotype of a mouse mutant in ATM-interactor (ATMIN; also known as ASCIZ) (Jurado et al., 2010).

To study how SHP-2 regulates tissue homeostasis in normal adults, we used a conditional SHP-2 mouse mutant in which loss of expression of SHP-2 was induced in multiple tissues in response to drug administration.

Conditional mouse mutants in which Phox2b27Ala was targeted to the RTN also lacked the ventilatory response to hypercapnia at birth but survived to adulthood and developed a partial hypercapnia response.

> We also tested known mouse mutants in the IIS pathway that affect lifespan.

Mouse mutants in which muscle development is affected provide useful systems for examining skeletogenesis in the presence of altered mechanical environments.

FMR1-null mouse mutants, in which the expression of FMRP is absent, have abnormally shaped spines on dendrites of Purkinje cells.

The merle phenotype shares similarities with Mitf mouse mutants in coat colour and ocular and hearing defects, and also with human Waardenburg patients.

Other published mouse mutants in which Tgfβ signaling is hampered do not develop an observable phenotype in the forebrain, as is the case for many TgfβRII conditional mutants (our own unpublished data, and Falk et al. 2008).