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Using a combination of analyses that included magnetic resonance imaging (MRI) and rotarod performance, we screened the offspring of ENU-treated mice and identified a heritable mouse mutant (designated p23-ST1) with clinical signs similar to NPH.
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Like ΔB, this mutant (designated ΔB234) was attenuated in Fg-deficient mice (Figure 3C).
This mutant designated SsrAwobble carried a U380C modification.
One of the rice mutants designated BKOS6 was characterized.
Here, we report two other rice LSE mutants, designated as LSE2 and LSE3.
Two point mutations each affected the seed sequences of miR-142-5p miR-142-5p miR-142-5pmutants-m4 in Fig. 1) or -3p (mutants designated -m1 and -m2 in Fig. 1).
Analyses of mutant mice designated lps2, which were generated by N-ethyl N-nitrosourea-induced random mutations, have also revealed that TRIF is an lps2 gene product that is essential for responses mediated by TLR3 and TLR4 [ 43].
The generated homozygous Recql4 mutant mice were designated Recql4HD.
Firstly, a construct that deleted the 3′ end fragment (region deleted in the DelB transgenic) was targeted and the mutant mice were designated ZRS3′del+LACZ/+ (Fig. 3A).
As mature podocytes lose proliferative capacity, a conditionally SV40 mutant tsA58-immortalized mouse podocyte line (designated as tsPC) was established from the Immortomouse over 20 years ago.
Seibler, J. et al. Rapid generation of inducible mouse mutants.
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