Sentence examples for mouse mutant confirmed from inspiring English sources

Complementation testing with a known Scn8a mouse mutant confirmed that this mutation is responsible for the Cloth-ears phenotype.

The mouse mutant confirms the involvement of cones and rods, with both showing a progressive decline in function from 3 months of age as determined by ERG responses; although, in keeping with the human disorder, the decline in cone-mediated responses was greater than the decline in rod-mediated responses once the age-related loss of rod function is taken into account.

Experiments with targeted mutants confirmed heteropolymers made of nestin and vimentin or nestin and GFAP in mouse cells [ 26- 28].

The reeler mouse mutant was used to confirm that the cortical alternation in MEMRI contrast was related to laminar architecture.

In summary, Tex19.1−/− mouse mutant that we generated confirms the spermatogenic phenotypes of a previously reported Tex19.1 mutant [15].

These double mutant mice were confirmed by the absence of both Neur1 and Neur2 transcripts in the adult brains (Figure 1C).

In situ hybridization experiments on coronal retinal sections showed a strong high V to low D gradient of Vax2 expression in Dicer mutant mice, confirming that the overall ventral polarity is still defined (Figure 8E, F).

Montages derived from low-magnification electron micrographs of the TMs of wild-type and Tecta mutant mice confirm that the marginal band remains closely associated with the main body of the TM in all three mutants despite being displaced medially in both the TectaL1820F,G1824D/+ and TectaC1837G/+ mice (Fig.  5E H).

Further investigation in human and mouse models confirmed that mutant SPOP blocks a process called called homology directed repair: this is the method that cells normally use to repair double-stranded DNA breaks.

To date, investigations of Lrig1 and Lrig3 mutant mouse phenotypes have confirmed that both molecules are important for aspects of development, but have done little to clarify their specific functions [24], [27].

The role of the eight genes during lens development was confirmed by studying spontaneous mouse mutants and genetically engineered mice with more or less similar ocular phenotypes as in human [12].