Sentence examples for mouse models whereas from inspiring English sources

IL-17A-dependent clearance of K. pneumoniae is impaired in monocyte- or TNF-depleted mouse models, whereas IL-17-producing ILC3s enhance monocyte-mediated bacterial clearance.

As predicted, M-T1 and M3 lost activity in Ccr2−/− mouse models, whereas M-T7 retained inhibitory activity.

These data are in agreement with other studies showing that contextual fear memory is early affected in APP transgenic mouse models, whereas spatial and reference memory deficits only become apparent after 6 8 months [ 16, 34, 35].

CD4+ cells are necessary and sufficient to cause cGvHD in mouse models, whereas cytotoxic CD8+ T cells are not required, in contrast to aGvHD (Rolink and Gleichmann, 1983; Rolink et al., 1983; Zhang et al., 2006).

Specifically, JQ1 is reported to have a maximum blood concentration of 0.84 μM in mouse models, whereas the compounds I-BET-762 and I-BET-151 reach maximum blood concentrations of 26 μM and 82 μM, respectively (Dawson et al., 2011).

One report suggested that opsin mislocalization may arise from the degeneration of the photoreceptors, regardless of the primary defect as demonstrated by others with unrelated disease mouse models, whereas the rhodopsin antibody (RET-P1) used by the other study is known to detect rhodopsin across multiple subcellular compartments of wild-type photoreceptors, including their cell bodies.

Regarding the unusual forms of bovine prions, L-type BSE was successfully transmitted to this ovine transgenic mouse model, whereas H-type BSE failed to transmit [19], and the reverse results were obtained in C57Bl/6 mice [9], [11].

Those studies used a mouse model, whereas we investigated primary human tendon tissues and tenocytes, thus our results are more likely to be relevant to human health.

The expression of a CAG repeat transcript from the antisense strand produces a toxic polyQ protein in a mouse model, whereas in HDL2 patients, polyQ proteins could not be detected despite the expression of CAG repeat RNA.

Furthermore, their study revealed that the deficiency in either IL-6, IL-1 or TNFα can inhibit the development and the progression of arthritis in this mouse model, whereas IL-10 deficiency leads to an exacerbation of the disease.

SRC-3-deficient mice exhibited more severe allergic response as demonstrated by a significant drop in body temperature and a delayed recovery period compared to wild-type mice in PSA mouse model, whereas no significant difference was observed between two kinds of mice in PCA mouse models.