Sentence examples for mouse models where from inspiring English sources

"We are looking at mouse models where something is mucked up.

I'll remind you of the mouse models, where we eliminate senescent cells.

mTORC1 is sensitive to low-dose rapamycin treatment in both cell culture and mouse models, where rapamycin directly binds to FKBP12 and disrupts the interaction between Raptor and mTOR, suppressing mTORC1 assembly and activation (Oshiro et al., 2004; Yip et al., 2010).

These results support previous findings in mouse models, where immunodominant epitopes are preferentially targeted by Tregs [43], [44], [45].

With regard to molecular mechanisms, it would be interesting to verify the roles of S100A8 and S100A9 genes in the skin regenerating processes after delivering radiation to specific genetically modified mouse models where those genes have been altered.

Though the downregulation of oncogenes may appear counterintuitive, it is to be expected in these particular mouse models, where the tumorigenic phenotype is mild and the tissue has been harvested in the pre-neoplastic regime.

In order to investigate a putative role for Lgl1 in OPC differentiation, we used a mouse model where Lgl1 knockout is targeted to NG2 cells28.

Using the GT-tg bigenic mouse model, where brain-selective Tat expression is induced by activation of a doxycycline (Dox) promotor, we tested the effects of Tat on cocaine (10 mg/kg, s.c.) induced locomotion and conditioned place preference (CPP).

Forbes and colleagues report on a population of hepatic progenitor cells that regenerate the adult liver in a mouse model where more than 98% of all hepatocytes are irreversibly damaged.

We demonstrate that an anti-MSLN antibody diminished adhesion formation in a mouse model where adhesions were induced by surgical ligation to form ischemic buttons and subsequent surgical abrasion of the peritoneum.

One potent lead K6a inhibitor, which was highly specific for K6a, was tested in a mouse model where reporter gene constructs were injected intradermally into mouse paw and luciferase activity was used as an in vivo readout.